Updated July 2026

DNA test
comparison tool

Select the companies you want to compare. See how they stack up on pricing, methodology, turnaround time, privacy, and key features.

Select companies to compare

Feature	23andMe	AncestryDNA	Nebula Genomics	MyHeritage DNA	FamilyTreeDNA	Living DNA	Dante Labs	Sequencing.com	TellmeGen	CircleDNA	CRI Genetics	Vitagene	Invitae	Natera	Guardant Health	Exact Sciences	Myriad Genetics	Ambry Genetics	GeneDx	Color Health	Genomind	Tempus	OneOme	GeneSight	Panorama (Natera)	MaterniT 21 PLUS	Unity (BillionToOne)
Category	Consumer DTC	Consumer DTC	Whole Genome	Consumer DTC	Consumer DTC	Consumer DTC	Whole Genome	WGS / Marketplace	Consumer DTC	Whole Exome	Consumer DTC	Consumer DTC	Clinical	Clinical	Clinical	Clinical	Clinical	Clinical	Clinical	Clinical DTC	Pharmacogenetic	Clinical + AI	Pharmacogenetic	Pharmacogenetic	Prenatal	Prenatal	Prenatal
Price Range	$99-$229	$99-$119	$299-$999	$49-$89	$79-$449	$79-$179	$299-$599	$399-$699	$169-$249	$349-$629	$99-$199	$49-$149	$250-$2,500	$349-$7,000	$5,000-$6,500	$599-$4,000	$500-$4,000	$300-$3,500	$1,000-$5,000	$249-$349	$399-$1,500	Insurance	$349-$599	Insurance	$349-$799	$299-$699	$249-$549
Test Type	Genotyping	Genotyping	30x WGS	Genotyping	Genotyping/Y/mtDNA	Genotyping	30x WGS	WGS/Upload	Genotyping	WES	Genotyping	Genotyping/Upload	Clinical NGS	Cell-free DNA	Liquid biopsy NGS	PCR/Gene expr	Clinical NGS	Clinical NGS	WES/WGS	Clinical NGS	PGx panel	NGS + AI	PGx panel	PGx panel	NIPT	NIPT	Carrier+NIPT
Turnaround	3-4 weeks	6-8 weeks	8-12 weeks	3-4 weeks	4-8 weeks	6-8 weeks	8-12 weeks	10-12 weeks	4-6 weeks	3-4 weeks	6-8 weeks	2-8 weeks	2-4 weeks	1-3 weeks	1-2 weeks	1-3 weeks	2-3 weeks	2-4 weeks	2-6 weeks	2-4 weeks	3-5 days	1-3 weeks	2-3 weeks	2-3 days	5-7 days	5-7 days	7-10 days
Health Reports	Yes (FDA-auth)	No	Yes (extensive)	Yes (limited)	No	Wellness only	Yes (extensive)	Yes	400+ conditions	500+ reports	Yes	Wellness	Clinical-grade	Clinical	Oncology	Oncology	Cancer-risk	Clinical	Clinical	Cancer+Heart	Medication	AI-driven	300+ meds	Mental health	Prenatal	Prenatal	Carrier+Prenatal
Ancestry Reports	2,000+ regions	1,800+ regions	Deep (WGS)	2,114 regions	90+ regions	150+ (UK detail)	WGS-based	Marketplace	Yes	Yes	50+ generations	No	No	No	No	No	No	No	No	No	No	No	No	No	No	No	No
Privacy Rating	3/5	3/5	5/5	3/5	4/5	5/5	4/5	4/5	4/5	3/5	3/5	4/5	4/5	4/5	4/5	4/5	4/5	5/5	5/5	4/5	4/5	4/5	4/5	4/5	4/5	4/5	4/5
Best For	Health + ancestry	Genealogy, DNA matches	Privacy, deep insights	European ancestry	Deep lineage	UK detail	EU WGS health	App marketplace	Multi-language	Exome premium	Timeline reports	Wellness	Medical-grade	Oncology/women	Cancer monitoring	Cancer screening	Hereditary cancer	Rare disease	Pediatric rare	Employer health	Mental health PGx	AI + clinical	300+ meds PGx	Depression meds	Early prenatal	Prenatal NIPT	Carrier screen

Key differences explained

Genotyping vs Whole Genome Sequencing

Genotyping (23andMe, AncestryDNA, MyHeritage) reads 600K-700K specific positions. WGS (Nebula, Dante Labs) reads all 3 billion base pairs, capturing rare variants and providing data that can be re-analyzed as science advances.

Bottom line: Genotyping is sufficient for ancestry and common health insights. WGS is better for comprehensive health analysis and future-proofing.

Why database size matters

Larger databases mean more DNA matches. AncestryDNA's 25M+ users means most testers find thousands of matches. Smaller databases mean fewer matches, especially for underrepresented ethnicities.

Strategy: Test with the largest database (AncestryDNA), then upload raw data to other platforms.

How to make your choice

Family history

AncestryDNA for the largest match database and family tree tools. Supplement with MyHeritage for European records.

View ancestry picks

Health insights

23andMe for FDA-authorized health reports at consumer pricing. Nebula or Dante Labs for comprehensive WGS health analysis.

View health picks

Both health and ancestry

23andMe Health + Ancestry offers the best combined package at $199. Pair AncestryDNA with Nebula WGS for maximum depth.

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