WGS Test

Find the right
DNA test

Compare 28 companies across whole genome sequencing, health screening, ancestry, and clinical testing.

Featured

TellmeGen

Spanish genotyping-based health and ancestry reports covering 400+ conditions. Drug response, inherited conditions, and personal traits.

Price $169-$249
Type Genotyping
Speed 4-6 weeks
Privacy 4/5
Visit TellmeGen

What is whole genome sequencing?

WGS reads all 3 billion base pairs of your DNA, capturing nearly 100% of your genetic code. Unlike genotyping chips that sample 0.02% at specific positions, WGS gives you the complete picture: rare variants, structural changes, and data that stays useful as science advances.

Most consumer tests (23andMe, AncestryDNA) use genotyping, which is sufficient for ancestry and common health insights. WGS is the choice for deep health analysis, rare disease screening, and future-proofing your genetic data.

3B
base pairs sequenced
100%
vs 0.02% genotyping
$299
starting consumer WGS
Lifetime
re-analysis as science advances

Genetic testing companies

Browse all 28 companies across four categories. Use the tags to filter by type.

Last updated July 2026

DTC & Consumer

Direct-to-consumer tests, no healthcare provider needed

23andMe

DTC

The most recognized name in consumer DNA testing. Offers health predisposition reports including BRCA1/BRCA2, carrier status screening, and ancestry composition across 2,000+ geographic regions. FDA-authorized health reports.

Price $99-$229
Type Genotyping
Speed 3-4 weeks
Privacy 3/5

AncestryDNA

DTC

The largest consumer DNA database with over 25 million users. Specializes in ethnicity estimates and family tree building with access to billions of historical records. Traits add-on for wellness and appearance insights.

Price $99-$119
Type Genotyping
Speed 6-8 weeks
Privacy 3/5

MyHeritage DNA

DTC

Strong alternative to AncestryDNA with a large European user base. Provides ethnicity estimates across 42 ethnicities and worldwide DNA matches. Integrated family tree builder and photo enhancement tools.

Price $49-$89
Type Genotyping
Speed 3-4 weeks
Privacy 3/5

FamilyTreeDNA

DTC

One of the oldest genetic genealogy companies, founded in 2000. Uniquely offers Y-DNA and mtDNA tests for deep paternal and maternal lineage tracing. Surname and geographical DNA projects unmatched in the industry.

Price $79-$449
Type Genotyping / Y / mtDNA
Speed 4-8 weeks
Privacy 4/5

Living DNA

DTC

UK-based company with exceptionally detailed regional breakdowns, especially within the British Isles (21 sub-regions). Combines ancestry with wellbeing reports. Data kept in EU under GDPR.

Price $79-$179
Type Genotyping
Speed 6-8 weeks
Privacy 5/5

Nebula Genomics

30x WGS

Offers 30x whole genome sequencing, capturing nearly 100% of your DNA versus the 0.02% that genotyping chips cover. Regularly updated reports as new research emerges. Blockchain-based consent management emphasizes data ownership.

Price $299-$999
Type WGS (30x)
Speed 8-12 weeks
Privacy 5/5

Dante Labs

WGS

European-based 30x WGS provider. Delivers comprehensive health report, pharmacogenomic analysis, and ancestry composition. Rare disease screening panels and nutrition-focused reports from full genetic data.

Price $299-$599
Type WGS (30x)
Speed 8-12 weeks
Privacy 4/5

Sequencing.com

DTC

Marketplace platform for sequencing and DNA analysis apps. 30x WGS available alongside raw data uploads from all major services. Purchase individual health, ancestry, or wellness reports through their marketplace.

Price $399-$699
Type WGS / Upload
Speed 10-12 weeks
Privacy 4/5

TellmeGen

DTC

Spanish genotyping-based health and ancestry reports covering 400+ conditions. Drug response, inherited conditions, and personal traits. Multi-language platform with a user-friendly results dashboard.

Price $169-$249
Type Genotyping
Speed 4-6 weeks
Privacy 4/5

CircleDNA

DTC

Hong Kong-based whole exome sequencing covering all protein-coding regions. 500+ reports spanning health risks, cancer screening, pharmacogenetics, ancestry, and wellness. Premium kit includes diet and fitness recommendations.

Price $349-$629
Type WES
Speed 3-4 weeks
Privacy 3/5

CRI Genetics

DTC

Combines ancestry and health reporting with user-friendly timelines. Proprietary algorithm delivers ancestry reports going back 50+ generations and health reports covering conditions, traits, and nutrition.

Price $99-$199
Type Genotyping
Speed 6-8 weeks
Privacy 3/5

Vitagene

DTC

Health and wellness focused. Accepts raw DNA data uploads from 23andMe, AncestryDNA, and others then generates personalized supplement, diet, and exercise recommendations. Action-oriented reports for daily health decisions.

Price $49-$149
Type Genotyping / Upload
Speed 2-8 weeks
Privacy 4/5

Clinical / Medical

Physician-ordered diagnostic and treatment-planning tests

Invitae

Clinical

Now part of Labcorp. Comprehensive genetic testing across cardiology, neurology, oncology, pediatrics, and reproductive health. Physician-ordered with genetic counseling. Tested over 4 million patients.

Price $250-$2,500
Type Clinical NGS panels
Speed 2-4 weeks
Privacy 4/5

Natera

Clinical

Cell-free DNA testing for oncology, women's health, and organ health. Signatera test is a pioneering personalized ctDNA assay for cancer monitoring. Panorama is one of the most widely used NIPT tests in the US.

Price $349-$7,000
Type Cell-free DNA
Speed 1-3 weeks
Privacy 4/5

Guardant Health

Clinical

Pioneer in liquid biopsy technology. Guardant360 analyzes ctDNA from a blood draw to identify genomic alterations across 74 genes. FDA-approved companion diagnostic helping oncologists select targeted therapies.

Price $5,000-$6,500
Type Liquid biopsy NGS
Speed 1-2 weeks
Privacy 4/5

Exact Sciences

Clinical

Known for Cologuard, the at-home colon cancer screening test. Oncotype DX analyzes gene activity in breast, colon, and prostate tumors to predict recurrence risk and chemotherapy benefit.

Price $599-$4,000
Type PCR / Gene expression
Speed 1-3 weeks
Privacy 4/5

Myriad Genetics

Clinical

Pioneer in hereditary cancer testing with 25+ years of experience. myRisk panel assesses 48 genes for hereditary cancers. BRACAnalysis was the first commercial test for BRCA1/2 mutations.

Price $500-$4,000
Type Clinical NGS panels
Speed 2-3 weeks
Privacy 4/5

Ambry Genetics

Clinical

Clinical lab specializing in hereditary disease testing. Panels for cancer, cardiovascular, neurological, and rare diseases. Known for rigorous variant interpretation and comprehensive gene coverage.

Price $300-$3,500
Type Clinical NGS panels
Speed 2-4 weeks
Privacy 5/5

GeneDx

Clinical

Leading provider of exome and genome sequencing for rare disease diagnosis. Analyzed over 500,000 clinical exomes. Focuses on pediatric and adult rare disease with WES and WGS ordered by specialists.

Price $1,000-$5,000
Type WES / WGS
Speed 2-6 weeks
Privacy 5/5

Color Health

Clinical

Population health genomics platform. Offers hereditary cancer and heart health genetic testing through employers and health systems. Includes genetic counseling and clinical-grade reports.

Price $249-$349
Type Clinical NGS
Speed 2-4 weeks
Privacy 4/5

Pharmacogenetic

How your genes affect medication response

Genomind

PGx

Professional pharmacogenetic testing service providing medication guidance across mental health, pain management, and cardiovascular drugs. Physician-ordered with clinical decision support tools.

Price $399-$1,500
Type PGx panel
Speed 3-5 days
Privacy 4/5

Tempus

PGx

AI-driven precision medicine platform combining genomic sequencing with clinical data analysis. Tempus offers comprehensive genomic profiling for oncology, cardiology, and psychiatry alongside pharmacogenomic guidance integrated with real-world evidence.

Price Insurance-covered
Type NGS + AI
Speed 1-3 weeks
Privacy 4/5

OneOme

PGx

Mayo Clinic-backed pharmacogenomic testing platform. Analyzes how genetic variations affect response to 300+ medications. Provides a personalized medication report for patients and clinicians.

Price $349-$599
Type PGx panel
Speed 2-3 weeks
Privacy 4/5

GeneSight

PGx

Myriad Genetics' pharmacogenomic test focused on mental health medications. Analyzes genetic variations affecting response to antidepressants, antipsychotics, and mood stabilizers. Widely used in psychiatric practice.

Price Insurance-covered
Type PGx panel
Speed 2-3 days
Privacy 4/5

Prenatal

Non-invasive prenatal testing and screening

Panorama (Natera)

Prenatal

Leading NIPT using SNP-based technology. Screens for common chromosomal abnormalities including trisomies 21, 18, 13, and sex chromosome aneuploidies. Also offers 22q11.2 deletion syndrome screening.

Price $349-$799
Type NIPT (SNP-based)
Speed 5-7 days
Privacy 4/5

MaterniT 21 PLUS

Prenatal

Labcorp's NIPT screening for fetal chromosomal abnormalities. Analyzes cell-free fetal DNA from maternal blood. Screens for trisomies 21, 18, 13, and sex chromosome conditions with high sensitivity and specificity.

Price $299-$699
Type NIPT
Speed 5-7 days
Privacy 4/5

Unity (BillionToOne)

Prenatal

Carrier screening and NIPT using molecular counting technology. Screens for cystic fibrosis, spinal muscular atrophy, and hemoglobinopathies alongside fetal aneuploidy screening. High accuracy at low fetal fractions.

Price $249-$549
Type Carrier + NIPT
Speed 7-10 days
Privacy 4/5

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